% pubman genre = article @article{item_3240007, title = {{A direct RT-qPCR approach to test large numbers of individuals for SARS-CoV-2}}, author = {Maricic, Tomislav and Nickel, Olaf and Ayinuer-Petri, Aximu and Essel, Elena and Gansauge, Marie-Theres and Kanis, Philipp and Macak, Dominik and Riesenberg, Stephan and Bokelmann, Lukas and Zeberg, Hugo and Meyer, Matthias and Borte, Stephan and P{\"a}{\"a}bo, Svante}, language = {eng}, issn = {1932-6203}, doi = {10.1371/journal.pone.0244824}, publisher = {Public Library of Science}, address = {San Francisco, CA}, year = {2020}, abstract = {{SARS-CoV-2 causes substantial morbidity and mortality in elderly and immunocompromised{\textless}br{\textgreater}individuals, particularly in retirement homes, where transmission from asymptomatic staff and visitors may introduce the infection. Here we present a cheap and fast approach to detect SARSCoV-2 in single or pooled gargle lavages ({\textquotedblleft}mouthwashes{\textquotedblright}). With this approach, we test all staff{\textless}br{\textgreater}at a nursing home daily over a period of three weeks in order to reduce the risk that the infection penetrates the facility. This or similar approaches could be implemented to protect hospitals, nursing homes and other institutions in this and future viral epidemics.}}, journal = {{PLoS One}}, volume = {15}, number = {12}, eid = {e0244824}, }